Cities need to modify and/or adapt their urban form, the distribution and location of services and learn how to handle the increasing complexity to face the most pressing challenges of this century. On these topics and the ones born during the last year, the scientific community is working in order to minimise negative effects on the environment, social and economic issues and people’s health. For these reasons, the three issues of the 14th volume will collect articles concerning the six topics addressed in 2020 and also a seventh concerning the effects on the urban areas related to the spread Covid-19 pandemic. In particular, TeMA Journal intends to propose articles that deal the effects of climate change, the ageing of the population, the reduction of energy consumption from fossil fuels, immigration flows from disadvantaged regions, innovation technology, the optimisation of land use and the impacts, in the short and long period, connected to the Covid-19 pandemic, with innovative methods, tools, techniques and practices.